学习经历、社会兼职及获奖情况

2014年本科毕业于宁夏大学生命科学学院生物科学（师范）专业，获理学学士学位。2019年博士毕业于清华大学生命科学学院生物学专业，获理学博士学位。迄今已在Nature, Nature Communications, PNAS等国际权威期刊发表多篇SCI论文。入选中国科协第五届“青年人才托举工程项目”。

研究领域

肿瘤代谢

代表性研究成果

[1] Le Li, Youxiang Mao, Lina Zhao, Lijia Li, Jinjun Wu, Mengjia Zhao, Wenjing Du, Li Yu and Peng Jiang*(2019).“p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis.”Nature 567(7747): 253-256. （被评为“2019年度中国医学重大进展”）

[2] Le Li#, Lijia Li#, Wei Li, Taiqi Chen, Bin Zou, Lina Zhao, Huili Wang, Xueying Wang, Lina Xu, Xiaohui Liu, Dong Wang, Bo Li, T. W. Mak, Wengjing Du*, Xiaolu Yang* and Peng Jiang*(2018). "TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation." Nat Communications 9(1): 4683.

[3] Longfei Deng, Pengbo Yao, Le Li, Fansen Ji, Shuang Zhao, Chang Xu, Xun Lan, and Peng Jiang*(2020). " p53-mediated control of aspartate/asparagine homeostasis dictates LKB1 activity and modulates cell fate decisions." Nat Communications 11(1): 1755 .

[4] Mengran Chen#; Han Pan#; Lingfei Sun#; Peng Shi#; Yikan Zhang; Le Li; Yuxing Huang; Jianhui Chen; Peng Jiang; Xianyang Fang; Congying Wu; Zhucheng Chen*(2020) Structure and regulation of human epithelial cell transforming 2 protein, Proc Natl Acad Sci USA 117:(2)1027-1035

[5] Jing Zhang, Adam J. Hirst, Fuyu Duan, Hui Qiu, Rujin Huang, Ying Ji, Lufeng Bai, Fengzhi Zhang, Darren Robinson, Mark Jones, Le Li, Peizhe Wang, Peng Jiang, Peter W. Andrews, Ivana Barbaric and Jie Na (2019). "Anti-apoptotic Mutations Desensitize Human Pluripotent Stem Cells to Mitotic Stress and Enable Aneuploid Cell Survival." Stem Cell Reports 12(3): 557-571.

#：第一作者    *：通讯作者